House's Jesse Spencer on Chase's Guilt, Cameron's Exit and the New Team

Most of the medical cases on DR HOUSE season DVD begin and end in a single episode, no matter how perplexing, complicated or rare. All that changed this season with the arrival — and death — of President Diabla (James Earl Jones), an African dictator accused of genocide and crimes against humanity. Dr. Chase's (Jesse Spencer) faith pushed him to choose to save a country rather than save a patient, and his role in the dictator's death has rocked his personal and professional worlds ever since.

Chase's fight to focus at work and his resistance to come clean with wife Cameron (Jennifer Morrison) is only about to intensify. As Spencer puts it, "the s--t's about to hit the fan." Spencer talked with TVGuide.com about how Chase's personal demons will affect his future at Princeton-Plainsboro, Morrison's on-screen exit and House's (Hugh Laurie) new team.

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